Prof. Steven Greenberg

Emerging Concepts in Vascular Cognitive Impairment


Submillimeter infarcts and cerebral small vessel disease are extraordinarily common and, by impairing cognitive function, produce arguably more disability than any other stroke type. Improvements in vascular risk are likely a major factor in recent slowdowns in the dementia epidemic, which nonetheless remains the looming public health threat of our time. Identifying disease-modifying therapies for the Vascular Contributions to Cognitive Impairment and Dementia (VCID) will depend on two pillars of knowledge: better biological understanding of the underlying small vessel diseases (primarily arteriolosclerosis and cerebral amyloid angiopathy) and better in vivo biomarkers.


Prof. Steven Greenberg - Bio

Dr. Greenberg is Professor of Neurology at Harvard Medical School, Vice Chair of Neurology for Faculty Development and Promotions, and holds the John J Conway Endowed Chair in Neurology at Massachusetts General Hospital. He is recipient of the 2017 American Heart Association William M. Feinberg Award for excellence in clinical stroke and has served in many national and international leadership roles in the fields of stroke and neurology including principle investigator for the NINDS VCID biomarkers consortium coordinating center, president of the International CAA Association, chair of the NIH Acute Neurologic Injury and Epilepsy study section, co-chair of the NINDS Alzheimer’s Disease-Related Dementias Summit subcommittee on vascular cognitive impairment, and chair of the American Heart Association International Stroke Conference. Dr. Greenberg has authored over 200 peer-reviewed research articles and over 70 chapters, reviews, and editorials in the areas of hemorrhagic stroke and small vessel brain disease. He received his undergraduate degree in Biochemistry from Harvard University and MD and PhD degrees from Columbia University under the graduate research training of Dr. James Schwartz. He performed internship at Pennsylvania Hospital, neurology residency at MGH, and post-doctoral fellowship at Brigham and Women’s Hospital under the training of Dr. Kenneth Kosik.